Clinical projects

Diabetic retinopathy
& AI

essential

An important obstacle to fight better diabetic retinopathy is the use of a classification based on old imaging techniques insufficient to finely predict the evolution of the disease. New imaging techniques (including ultra widefield fundus photography, optical coherence tomography, OCT-angiography) are already available. They generate vast new valuable data, that combined with other data and with a new adapted classification can provide a more accurate evaluation of diabetic retinopathy risks. This will be the based to the development of a more personalized preventive treatment that can help maintain the full vision of diabetic patients.

innovative

Our difference is to use new technologies to develop a medical decision support tool.

The combination of diabetology and ophthalmology knowledge, industrial R&D and academics skills, large cohort of patients with companies that are already world class leaders creates a unique opportunity to make this project a success.

ambitious

We will use a unique combination of clinical information of patients, the best modalities of retinal imaging, and our home-made artificial intelligence to provide ophthalmologists with a decision aid tool for improved diagnosis and risk evaluation, allowing them to take an easier, quicker, and better decision for their patients. Per design, instead of increasing costs and inequity EviRed should help reducing unnecessary treatment or burden and ease the spread of expertise to where it is needed.

EviRed
Database 1

Database 1 is the first of EviRed clinical trials.

Aim:  To recruit a cohort of 5000 patients, in 10 different French sites scattered across the country, and follow them for at least 2 years to collect data needed to train and validate developed algorithms.

EviRed
Study Group

They participate and recruit for the project Evired DataBase 1

Sponsor: Assistance Publique – Hôpitaux de Paris (AP-HP)

Sites City Principal Investigator
001- CHU LARIBOISIERE PARIS Aude COUTURIER
002 - CHU DIJON DIJON Catherine CREUZOT-GARCHER
003 - CHU BORDEAUX BORDEAUX Jean-François KOROBELNIK
004 - CHU LYON CROIX ROUSSE LYON Laurent KODJIKIAN
005 - CHU AVICENNE BOBIGNY Audrey GIOCANTI
006 - CIC CRETEIL CRÉTEIL Alexandra MIERE
007 - CHU PITIE PARIS Sarah TOUHAMI
008 – BROCA / MUTUELLE GENERALE PARIS Pascale MASSIN
009 - CHU BREST BREST Béatrice COCHENER
010 - HÔPITAL DES 15-20 PARIS Michel PAQUES
011 - CHU NANTES NANTES Michel WEBER
012 - FONDATION ROTHSCHILDPARIS Sophie BONNIN
013 - CENTRE MONTICELLI PARADIS MARSEILLE Pierre GASCON
014 - CHU NICE NICE Stéphanie BAILLIF

EviRed
Scientific Advisory
Board members

Pr. Pearse Keane

Professor Pearse Keane is a retinal specialist at Moorfields Eye Hospital in London, UK, and Professor of Artificial Medical Intelligence at University College London (UCL). He is working on developing artificial intelligence (AI) algorithms and their application in detection and treatment of retinal diseases.

Dr. Richard Spaide

Doctor Richard Spaide is in private practice at the Vitreous, Retina, Macula Consultants of New York. He is specialized in retinal diseases and focused his researches on imaging methods (OCT, OCT-A). He has also developed surgical ophthalmic instruments. He is the first author with the most highly cited articles in the top 100 list published between 2010 and 2020.

Pr. Adnan Tufail

Professor Adnan Tufail is based at Moorfields Eye Hospital and at Institute of Ophthalmology at UCL (University College London), he specialized in medical retina disorders (AMD, diabetic retinopathy and myopic degeneration) and cataract surgery.

Pr. Nadia Waheed

Nadia Waheed is Professor of Ophthalmology and Director of OCT research at Tufts University School of Medicine in Boston, USA and is the Chief Medical Officer Gyroscope Therapeutics. Her research is focused on novel imaging modalities (OCT, OCT-A) and their applications in AMD and Diabetic Retinopathy, development of endpoints for clinical trials, as well as gene therapy in ocular disease.

Pr. Sebastian Wolf

Professor Sebastian Wolf is the chairman of the Department of Ophthalmology in Inselspital at University of Bern, Switzerland. His main areas of researches are age-related macular degeneration, diabetic retinopathy, retinal vein occlusion, imaging and vitreoretinal surgery. He is also Director of the Bern Photographic Reading Center.

Dr. Jean Zetlaoui

Dr Jean Zetlaoui is now a consultant in Medical Sciences & Clinical Development. He started his career as Associate Professor in Anaesthesiology & Intensive Care, and then occupied several managing positions in international companies (Sanofi, Nestlé Health Science, Novartis…). He knows well the French healthcare environment and its challenges.

EviRed
ancillary studies

EviRed is also the base for ancillary studies.

Coming soon...

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